Skip to content

Health Resources

Health Resources

This document represents a collection of resources from the Technical Advisory Panel (TAP) as an addition to those referenced in the RFP document. These are intended to provide assistance in obtaining relevant background information, preparing a competitive proposal, and completing quality work.   

These resources are not intended to be exhaustive nor authoritative. This document does not represent an endorsement of work by the Lacuna Fund Secretariat, the TAP, or individual members.   

Resources for Proposals in Antimicrobial Resistance (AMR) 

ACADEMIC PAPERS 

  • A Public Health Action Plan to Combat Antimicrobial Resistance, in The Resistance Phenomenon in Microbes and Infectious Disease Vectors: Implications for Human Health and Strategies for Containment: Workshop Summary. Institute of Medicine (US) Forum on Emerging Infections; Knobler SL, Lemon SM, Najafi M, et al., editors. 
  • Shortage of essential antimicrobials: a major challenge to global health security. Shafiq, Nusrat, Avaneesh Kumar Pandey, Samir Malhotra, Alison Holmes, Marc Mendelson, Rohit Malpani, Manica Balasegaram, and Esmita Charani. BMJ global health 6, no. 11 (2021): e006961. The authors map common drivers for antimicrobial shortages and propose strategies for rethinking the regulation, supply and pricing of antimicrobials to secure their sustainable access across diverse healthcare systems and to help minimise the unintended consequences of weak and ineffective supply chains. 

 

NON-ACADEMIC PAPERS 

  • Antimicrobial resistance and the great divide: inequity in priorities and agendas between the Global North and the Global South threatens global mitigation of antimicrobial resistance (2024). Mendelson, Marc, Ramanan Laxminarayan, Direk Limmathurotsakul, Samuel Kariuki, Martha Gyansa-Lutterodt, Esmita Charani, Sanjeev Singh, Kamini Walia, Ana C. Gales, and Mirfin Mpundu. The authors argue that the diverging resource availabilities, needs, and priorities of the Global North and the Global South in terms of the actions required to mitigate the antimicrobial resistance pandemic are a direct threat to success. The evidence suggests a need to prioritise and support infection prevention interventions (ie, clean water and safe sanitation, increased vaccine coverage, and enhanced infection prevention measures for food production in the Global South contrary to the focus on research and development of new antibiotics in the Global North) and to recalibrate global funding resources to address this need. 
  • Ethics and governance of artificial intelligence for health. World Health Organization 2024. Chief Scientist and Science Division (SCI), Health Ethics & Governance (HEG). This guidance addresses one type of generative AI, large multi-modal models (LMMs), which can accept one or more type of data input and generate diverse outputs that are not limited to the type of data fed into the algorithm. It has been predicted that LMMs will have wide use and application in health care, scientific research, public health and drug development.  

 

PLATFORMS, CONSORTIA AND INITIATIVES 

  • AWaRe (Access, Watch and Reserve): WHO initiative that, since 2017, categorizes antibiotics into three groups, Access, Watch and Reserve. 
  • The Resource Centre at the Global Antimicrobial Resistance and Use Surveillance System (GLASS), convened by WHO. GLASS was created to strengthen knowledge through surveillance and research, and to continue filling knowledge gaps, with the aim to inform strategies at all levels. GLASS provides a standardized approach to the collection, analysis, interpretation and sharing of data by countries and seeks to actively support capacity building and monitor the status of existing and new national surveillance systems. Furthermore, GLASS promotes a shift from surveillance approaches based solely on laboratory data to a system that includes epidemiological, clinical, and population-level data. 
  • AIRCHECK The Artificial Intelligence Ready CHEmiCal Knowledge-base (AIRCHECK) is an open platform developed to share large-scale, publicly accessible chemical activity data. Specifically, AIRCHECK consists of a collection of datasets generated from large DNA-encoded library (DEL) screenings of various protein targets. AIRCHECK is developed and populated as a collaboration between the Structural Genomics Consortium, University of Toronto, University of North Carolina, X-Chem, and HitGen.    
  • HATUA consortium: Holistic Approach to Unravel Antibacterial Resistance in East Africa  
  • Public Health Guides at the National Library of Medicine. Although not necessarily related to AMR, this platform holds interesting resources that might be helpful for applicants interested in deepening their public health perspective. 

Resources for Proposals in Sexual, Reproductive and Maternal Health and Rights